Publications

See a list of all publications here.

2021

Klatt NR, Broedlow C, Osborn JM, Gustin AT, Dross S, O'Connor MA, Coronado E, Barnette P, Hensley-McBain T, Zevin AS, Muir R, Roederer A, Wangari S, Iwayama N, Ahrens CY, Smedley J, Moats C, Lynch RM, Haddad EK, Haigwood NL, Fuller DH, Manuzak JA.
Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques.
NPJ Vaccines. 2021 Mar 11;6(1):34. doi: 10.1038/s41541-021-00298-4. PubMed PMID: 33707443.

Kinloch NN, Ren Y, Conce Alberto WD, Dong W, Khadka P, Huang SH, Mota TM, Wilson A, Shahid A, Kirkby D, Harris M, Kovacs C, Benko E, Ostrowski MA, Del Rio Estrada PM, Wimpelberg A, Cannon C, Hardy WD, MacLaren L, Goldstein H, Brumme CJ, Lee GQ, Lynch RM, Brumme ZL, Jones RB.
HIV-1 diversity considerations in the application of the Intact Proviral DNA Assay (IPDA).
Nat Commun. 2021 Jan 8;12(1):165. doi: 10.1038/s41467-020-20442-3. PubMed PMID: 33420062.

2020

Ren Y, Korom M, Ward AR, Truong R, Chan D, Huang SH, Kovacs CM, Benko E, Safrit JT, Lee J, Garbán H, Lynch R, Jones RB.
Relationships between Neutralization, Binding, and ADCC of Broadly Neutralizing Antibodies against Reservoir HIV.
J Virol. 2020 Dec 22;95(2). doi: 10.1128/JVI.01808-20. Print 2020 Dec 22. PubMed PMID: 33115874.

Powell AB, Ren Y, Korom M, Saunders D, Hanley PJ, Goldstein H, Nixon DF, Bollard CM, Lynch RM, Jones RB, Cruz CRY.
Engineered Antigen-Specific T Cells Secreting Broadly Neutralizing Antibodies: Combining Innate and Adaptive Immune Response against HIV.
Mol Ther Methods Clin Dev. 2020 Dec 11;19:78-88. doi: 10.1016/j.omtm.2020.08.015. eCollection 2020 Dec 11. PubMed PMID: 33005704.

Wilson A, Lynch RM.
Embracing diversity: how can broadly neutralizing antibodies effectively target a diverse HIV-1 reservoir?
Curr Opin Pharmacol. 2020 Oct;54:173-178. doi: 10.1016/j.coph.2020.10.004. Epub 2020 Nov 12. Review. PubMed PMID: 33189993.

Cale EM, Bai H, Bose M, Messina MA, Colby DJ, Sanders-Buell E, Dearlove B, Li Y, Engeman E, Silas D, O'Sullivan AM, Mann B, Pinyakorn S, Intasan J, Benjapornpong K, Sacdalan C, Kroon E, Phanuphak N, Gramzinski R, Vasan S, Robb ML, Michael NL, Lynch RM, Bailer RT, Pagliuzza A, Chomont N, Pegu A, Doria-Rose NA, Trautmann L, Crowell TA, Mascola JR, Ananworanich J, Tovanabutra S, Rolland M.
Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.
J Clin Invest. 2020 Jun 1;130(6):3299-3304. doi: 10.1172/JCI134395. PubMed PMID: 32182219.

2019

Rawi R, Mall R, Shen CH, Farney SK, Shiakolas A, Zhou J, Bensmail H, Chun TW, Doria-Rose NA, Lynch RM, Mascola JR, Kwong PD, Chuang GY.
Accurate Prediction for Antibody Resistance of Clinical HIV-1 Isolates.
Sci Rep. 2019 Oct 11;9(1):14696. doi: 10.1038/s41598-019-50635-w. PubMed PMID: 31604961.

Bar KJ, Coronado E, Hensley-McBain T, O'Connor MA, Osborn JM, Miller C, Gott TM, Wangari S, Iwayama N, Ahrens CY, Smedley J, Moats C, Lynch RM, Haddad EK, Haigwood NL, Fuller DH, Shaw GM, Klatt NR, Manuzak JA.
Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus Macaques Results in Persistent Viral Replication and Induces Intestinal Immunopathology.
J Virol. 2019 Sep 15;93(18). doi: 10.1128/JVI.00372-19. Print 2019 Sep 15. PubMed PMID: 31217249.

Yu WH, Su D, Torabi J, Fennessey CM, Shiakolas A, Lynch R, Chun TW, Doria-Rose N, Alter G, Seaman MS, Keele BF, Lauffenburger DA, Julg B.
Predicting the broadly neutralizing antibody susceptibility of the HIV reservoir.
JCI Insight. 2019 Sep 5;4(17). doi: 10.1172/jci.insight.130153. PubMed PMID: 31484826.

Rico-Mendoza A, Alexandra PR, Chang A, Encinales L, Lynch R.
Co-circulation of dengue, chikungunya, and Zika viruses in Colombia from 2008 to 2018.
Rev Panam Salud Publica. 2019;43:e49. doi: 10.26633/RPSP.2019.49. eCollection 2019. PubMed PMID: 31171921.

Flerin NC, Bardhi A, Zheng JH, Korom M, Folkvord J, Kovacs C, Benko E, Truong R, Mota T, Connick E, Jones RB, Lynch RM, Goldstein H.
Establishment of a Novel Humanized Mouse Model To Investigate In Vivo Activation and Depletion of Patient-Derived HIV Latent Reservoirs.
J Virol. 2019 Mar 15;93(6). doi: 10.1128/JVI.02051-18. Print 2019 Mar 15. PubMed PMID: 30626677.

Lynch RM, Mantus G, Encinales L, Pacheco N, Li G, Porras A, Mendoza AR, Peng J, Rengifo-Pardo M, Cruz MM, Harris E, Bethony JM, Simon GL, Chang AY.
Augmented Zika and Dengue Neutralizing Antibodies Are Associated With Guillain-Barré Syndrome.
J Infect Dis. 2019 Jan 1;219(1):26-30. doi: 10.1093/infdis/jiy466. PubMed PMID: 30113672.

2018

Ho CY, Castillo N, Encinales L, Porras A, Mendoza AR, Lynch R, Nemirovsky A, Mantus G, DeBiasi RL, Bethony JM, Simon GL, Chang AY.
Second-trimester Ultrasound and Neuropathologic Findings in Congenital Zika Virus Infection.
Pediatr Infect Dis J. 2018 Dec;37(12):1290-1293. doi: 10.1097/INF.0000000000002080. PubMed PMID: 30408008.

Ren Y, Korom M, Truong R, Chan D, Huang SH, Kovacs CC, Benko E, Safrit JT, Lee J, Garbán H, Apps R, Goldstein H, Lynch RM, Jones RB.
Susceptibility to Neutralization by Broadly Neutralizing Antibodies Generally Correlates with Infected Cell Binding for a Panel of Clade B HIV Reactivated from Latent Reservoirs.
J Virol. 2018 Dec 1;92(23). doi: 10.1128/JVI.00895-18. Print 2018 Dec 1. PubMed PMID: 30209173.